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PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating

The RNA genome of human immunodeficiency virus type 1 (HIV-1) is enclosed in a cone-shaped capsid shell that disassembles following cell entry via a process known as uncoating. During HIV-1 infection, the capsid is important for reverse transcription and entry of the virus into the target cell nucle...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Rankovic, Sanela, Ramalho, Ruben, Aiken, Christopher, Rousso, Itay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158434/
https://ncbi.nlm.nih.gov/pubmed/30089694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00845-18
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