Inhibition of deoxynucleoside kinases in human thymocytes prevents dATP accumulation and induction of apoptosis

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• Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases,
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  Cyhoeddwyd: (2008)
• Adenosine kinase inhibition promotes survival of fetal adenosine deaminase–deficient thymocytes by blocking dATP accumulation
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• Human αβ and γδ Thymocyte Development: TCR Gene Rearrangements, Intracellular TCRβ Expression and γδ Developmental Potential – Differences between Men and Mice,
  gan: Joachims, Michelle L., et al.
  Cyhoeddwyd: (2006)
• ATP depletion inhibits glucocorticoid-induced thymocyte apoptosis.
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  Cyhoeddwyd: (1997)
• Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation.
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  Cyhoeddwyd: (1980)