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Vesicular monoamine transporter 2: Role as a novel target for drug development

In the central nervous, system, vesicular monoamine transporter 2 (VMAT2) is the only transporter that moves cytoplasmic dopamine (DA) into synaptic vesicles for storage and subsequent exocytotic release. Pharmacologically enhancing DA sequenstration by VMAT2, and thus preventing the oxidation of DA...

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Main Authors: Zheng, Guangrong, Dwoskin, Linda P., Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751365/
https://ncbi.nlm.nih.gov/pubmed/17233532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080478
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