Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes

INTRODUCTION: Germline mutations in the BRCA1 and BRCA2 genes account for a considerable fraction of familial predisposition to breast cancer. Somatic mutations in BRCA1 and BRCA2 have not been found and the involvement of these genes in sporadic tumour development therefore remains unclear. METHODS...

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Main Authors: Stefansson, Olafur Andri, Jonasson, Jon Gunnlaugur, Johannsson, Oskar Thor, Olafsdottir, Kristrun, Steinarsdottir, Margret, Valgeirsdottir, Sigridur, Eyfjord, Jorunn Erla
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750106/
https://ncbi.nlm.nih.gov/pubmed/19589159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2334
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