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Transfer of Rolf S3-S4 Linker to hERG Eliminates Activation Gating but Spares Inactivation
Studies in Shaker, a voltage-dependent potassium channel, suggest a coupling between activation and inactivation. This coupling is controversial in hERG, a fast-inactivating voltage-dependent potassium channel. To address this question, we transferred to hERG the S3-S4 linker of the voltage-independ...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Biophysical Society
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749759/ https://ncbi.nlm.nih.gov/pubmed/19720020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.05.060 |
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