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Phosphatidylinositol-4,5-Bisphosphate (PIP(2)) Stabilizes the Open Pore Conformation of the Kv11.1 (hERG) Channel
Phosphatidylinositol-4,5-bisphosphate (PIP(2)) is a phospholipid that has been shown to modulate several ion channels, including some voltage-gated channels like Kv11.1 (hERG). From a biophysical perspective, the mechanisms underlying this regulation are not well characterized. From a physiological...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Biophysical Society
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920645/ https://ncbi.nlm.nih.gov/pubmed/20712994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.013 |
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