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RNAi Screening in Drosophila Cells Identifies New Modifiers of Mutant Huntingtin Aggregation
The fruitfly Drosophila melanogaster is well established as a model system in the study of human neurodegenerative diseases. Utilizing RNAi, we have carried out a high-throughput screen for modifiers of aggregate formation in Drosophila larval CNS-derived cells expressing mutant human Huntingtin exo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748703/ https://ncbi.nlm.nih.gov/pubmed/19789644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007275 |
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