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A Genomewide RNA Interference Screen for Modifiers of Aggregates Formation by Mutant Huntingtin in Drosophila

Protein aggregates are a common pathological feature of most neurodegenerative diseases (NDs). Understanding their formation and regulation will help clarify their controversial roles in disease pathogenesis. To date, there have been few systematic studies of aggregates formation in Drosophila, a mo...

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Detalles Bibliográficos
Main Authors: Zhang, Sheng, Binari, Richard, Zhou, Rui, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865916/
https://ncbi.nlm.nih.gov/pubmed/20100940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.112516
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