Načítá se...

Synthesis of 2-Chloro-N(6)-Substituted-4′-thioadenosine-5′-N,N-dialkyluronamides as Potent and Selective A(3) Adenosine Receptor Antagonists

The highly selective A(3) receptor agonist, 4′-thio-Cl-IB-MECA was successfully converted into selective A(3) receptor antagonists by appending a second N-alkyl group on the 5′-uronamide position. This result indicates that the hydrogen bonding ability of the 5′-uronamide is essential for the confor...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Choi, Won Jun, Lee, Hyuk Woo, Hou, Xiyan, Kim, Hea OK, Jacobson, Kenneth A., Jeong, Lak Shin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748263/
https://ncbi.nlm.nih.gov/pubmed/18776545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nass/nrn326
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!