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Regulation of Repair Choice: Cdk1 Suppresses Recruitment of End Joining Factors at DNA Breaks

Cell cycle plays a crucial role in regulating the pathway used to repair DNA double-strand breaks (DSBs). In Saccharomyces cerevisiae, homologous recombination is primarily limited to non-G(1) cells as the formation of recombinogenic single-stranded DNA requires CDK1-dependent 5′ to 3′ resection of...

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Detalhes bibliográficos
Main Authors: Zhang, Yu, Shim, Eun Yong, Davis, Melody, Lee, Sang Eun
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748135/
https://ncbi.nlm.nih.gov/pubmed/19699692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.07.007
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