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ZNF281 is recruited on DNA breaks to facilitate DNA repair by non-homologous end joining

Efficient repair of DNA double-strand breaks (DSBs) is of critical importance for cell survival. Although non-homologous end joining (NHEJ) is the most used DSBs repair pathway in the cells, how NHEJ factors are sequentially recruited to damaged chromatin remains unclear. Here, we identify a novel r...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Nicolai, Sara, Mahen, Robert, Raschellà, Giuseppe, Marini, Alberto, Pieraccioli, Marco, Malewicz, Michal, Venkitaraman, Ashok R., Melino, Gerry
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976523/
https://ncbi.nlm.nih.gov/pubmed/31570788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-1028-7
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