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Synthesis and Evaluation of an RNA Editing Substrate Bearing 2’-Deoxy-2’-mercaptoadenosine
The RNA-editing adenosine deaminases (ADARs) catalyze deamination of adenosine to inosine in double stranded structure found in various RNA substrates, including mRNAs. Here we describe the synthesis of a phosphoramidite of 2’-deoxy-2'-mercaptoadenosine and its incorporation into an ADAR substr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747504/ https://ncbi.nlm.nih.gov/pubmed/19219738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770902736459 |
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