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How do ADARs bind RNA? New protein-RNA structures illuminate substrate recognition by the RNA editing ADARs

Deamination of adenosine in RNA to form inosine has wide ranging consequences on RNA function including amino acid substitution to give proteins not encoded in the genome. What determines which adenosines in an mRNA are subject to this modification reaction? The answer lies in an understanding of th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Bioessays
मुख्य लेखकों: Thomas, Justin M., Beal, Peter A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501306/
https://ncbi.nlm.nih.gov/pubmed/28217931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600187
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