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Selective Recognition of RNA Substrates by ADAR Deaminase Domains

Adenosine deamination is one of the most prevalent post-transcriptional modifications in mRNA and is catalyzed by ADAR1 and ADAR2 in humans. ADAR1 and ADAR2 have different substrate selectivity, which is believed to mainly originate from the proteins’ deaminase domains (hADAR1d and hADAR2d, respecti...

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Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Wang, Yuru, Park, SeHee, Beal, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898644/
https://ncbi.nlm.nih.gov/pubmed/29457714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01100
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