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Selective Recognition of RNA Substrates by ADAR Deaminase Domains

Adenosine deamination is one of the most prevalent post-transcriptional modifications in mRNA and is catalyzed by ADAR1 and ADAR2 in humans. ADAR1 and ADAR2 have different substrate selectivity, which is believed to mainly originate from the proteins’ deaminase domains (hADAR1d and hADAR2d, respecti...

詳細記述

保存先:
書誌詳細
出版年:Biochemistry
主要な著者: Wang, Yuru, Park, SeHee, Beal, Peter A.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898644/
https://ncbi.nlm.nih.gov/pubmed/29457714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01100
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