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Selective Recognition of RNA Substrates by ADAR Deaminase Domains
Adenosine deamination is one of the most prevalent post-transcriptional modifications in mRNA and is catalyzed by ADAR1 and ADAR2 in humans. ADAR1 and ADAR2 have different substrate selectivity, which is believed to mainly originate from the proteins’ deaminase domains (hADAR1d and hADAR2d, respecti...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5898644/ https://ncbi.nlm.nih.gov/pubmed/29457714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01100 |
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