Synthesis and Antiproliferative Evaluation of 2-Deoxy-N-glycosylbenzotriazoles/imidazoles

A series of 2-deoxy-2-iodo-α-d-mannopyranosylbenzotriazoles was synthesized using the benzyl, 4,6-benzylidene and acetyl protected D-glucal in the presence of N-iodosuccinimide (NIS). Subsequent removal of the iodine at the C-2 position using tributyltin hydride under free radical conditions afforde...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Garton, Caleigh S., DeRose, Noelle K., Dominguez, Dylan, Turbi-Henderson, Maria L., Lehr, Ashley L., Padilla, Ashley D., Twining, Scott D., Casas, Stephanie, Alozie, Chidozie O., Gucwa, Azad L., Elshaer, Mohammed R., De Castro, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234545/
https://ncbi.nlm.nih.gov/pubmed/34205324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26123742
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