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Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma

We have previously reported substituted 2-aryl-thiazolidine-4-carboxylic acid amides as potent and selective antiproliferative agents for melanoma. To understand the importance of the thiazolidine ring and to reduce potential complications associated with the two chiral centers, we designed and synt...

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Hlavní autoři: Chen, Jianjun, Wang, Zhao, Lu, Yan, Dalton, James T., Miller, Duane D., Li, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494854/
https://ncbi.nlm.nih.gov/pubmed/18477505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.04.073
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