C5a RECEPTOR (C5aR) CHIMERAS REVEAL THE IMPORTANCE OF LIPID-FACING RESIDUES IN TRANSPORT COMPETENCE

Residues that mediate helix-helix interactions within the seven transmembranes (TM) of G protein-coupled receptors are important for receptor biogenesis and the receptor switch mechanism. In contrast, the residues directly contacting the lipid bilayer have only recently garnered attention as potenti...

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Detalhes bibliográficos
Main Authors: Klco, Jeffery M., Sen, Saurabh, Hansen, Jakob L., Lyngsø, Christina, Nikiforovich, Gregory V., Sheikh, Soren P., Baranski, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747494/
https://ncbi.nlm.nih.gov/pubmed/19459935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2009.07002.x
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