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Simplified modeling approach suggests structural mechanisms for constitutive activation of the C5a receptor
Molecular modeling of conformational changes occurring in the transmembrane (TM) region of the complement factor 5a receptor (C5aR) during receptor activation was performed by comparing two constitutively active mutants (CAMs) of C5aR, NQ (I124N/L127Q) and F251A, to those of the wild-type C5aR and N...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072438/ https://ncbi.nlm.nih.gov/pubmed/21287612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22918 |
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