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Regulation of Autophagy in Cartilage: HIF-2 Suppresses Chondrocyte Autophagy

OBJECTIVE: We have previously demonstrated that the transcription factor, HIF-1, promoted the onset of autophagy in chondrocytes. The overall goal of this study was to test the hypothesis that another HIF family transcription factor, HIF-2, modulated the induction of autophagy by chondrocytes. METHO...

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Detalhes bibliográficos
Main Authors: Bohensky, Jolene, Terkhorn, Shawn P, Freeman, Theresa, Adams, Christopher S, Garcia, Joseph, Shapiro, Irving M, Srinivas, Vickram
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747039/
https://ncbi.nlm.nih.gov/pubmed/19404942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24444
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