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Iron and the translation of the amyloid precursor protein (APP) and ferritin: riboregulation against neural oxidative damage in Alzheimer’s disease
The essential metals iron, zinc and copper deposit near the Aβ (amyloid β-peptide) plaques in the brain cortex of AD (Alzheimer’s disease) patients. Plaque-associated iron and zinc are in neurotoxic excess at 1 mM concentrations. APP (amyloid precursor protein) is a single transmembrane metalloprote...
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746665/ https://ncbi.nlm.nih.gov/pubmed/19021541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0361282 |
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