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A Twist on Heme Signaling
Proteins in the H-NOX family act as sensors of NO or O(2). This family includes soluble guanylate cyclase, sGC, the NO sensor that is responsible for vasodilation and neurotransmission in mammals. The crystal structures of bacterial H-NOX domains have revealed a highly distorted heme cofactor. This...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745536/ https://ncbi.nlm.nih.gov/pubmed/19032089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800269h |
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