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Mechanism of the CO-sensing heme protein CooA: new insights from the truncated heme domain and UVRR spectroscopy

The bacterial CO-sensing heme protein CooA activates expression of genes whose products perform CO-metabolism by binding its target DNA in response to CO binding. The required conformational change has been proposed to result from CO-induced displacement of the heme and of the adjacent C-helix, whic...

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Bibliografiske detaljer
Main Authors: Ibrahim, Mohammed, Kuchinskas, Michael, Youn, Hwan, Kerby, Robert L., Roberts, Gary P., Poulos, Thomas L., Spiro, Thomas G.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096632/
https://ncbi.nlm.nih.gov/pubmed/17720248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2007.07.010
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