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Zebrafish Hagoromo mutants upregulate fgf8 post-embryonically and develop neuroblastoma

We screened an existing collection of zebrafish insertional mutants for cancer susceptibility by histological examination of heterozygotes at two years of age. As most mutants had no altered cancer predisposition, this provided the first comprehensive description of spontaneous tumor spectrum and fr...

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Detalhes bibliográficos
Main Authors: Amsterdam, Adam, Lai, Kevin, Komisarczuk, Anna Z, Becker, Thomas S, Bronson, Roderick T., Hopkins, Nancy, Lees, Jacqueline A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744123/
https://ncbi.nlm.nih.gov/pubmed/19531571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0555
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