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A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression

BACKGROUND: Craniofacial birth defects result from defects in cranial neural crest (NC) patterning and morphogenesis. The vertebrate craniofacial skeleton is derived from cranial NC cells and the patterning of these cells occurs within the pharyngeal arches. Substantial efforts have led to the ident...

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Detalhes bibliográficos
Main Authors: Nissen, Robert M, Amsterdam, Adam, Hopkins, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523201/
https://ncbi.nlm.nih.gov/pubmed/16759393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-6-28
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