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A genetic screen for zebrafish mutants with hepatic steatosis identifies a locus required for larval growth

In a screen for zebrafish larval mutants with excessive liver lipid accumulation (hepatic steatosis), we identified harvest moon (hmn). Cytoplasmic lipid droplets, surrounded by multivesicular structures and mitochondria whose cristae appeared swollen, are seen in hmn mutant hepatocytes. Whole body...

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Podrobná bibliografie
Vydáno v:J Anat
Hlavní autoři: Hugo, Sarah E., Schlegel, Amnon
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314394/
https://ncbi.nlm.nih.gov/pubmed/27976367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12570
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