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A genetic screen for zebrafish mutants with hepatic steatosis identifies a locus required for larval growth

In a screen for zebrafish larval mutants with excessive liver lipid accumulation (hepatic steatosis), we identified harvest moon (hmn). Cytoplasmic lipid droplets, surrounded by multivesicular structures and mitochondria whose cristae appeared swollen, are seen in hmn mutant hepatocytes. Whole body...

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Detalhes bibliográficos
Publicado no:J Anat
Main Authors: Hugo, Sarah E., Schlegel, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314394/
https://ncbi.nlm.nih.gov/pubmed/27976367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joa.12570
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