Zebrafish Mutants with Disrupted Early T cell and Thymus Development Identified in Early Pressure Screen

Generation of mature T lymphocytes requires an intact hematopoietic stem cell compartment and functional thymic epithelium. We used the zebrafish (Danio rerio) to isolate mutations that affect the earliest steps in T lymphopoiesis and thymic organogenesis. Here we describe the results of a genetic s...

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Bibliografiska uppgifter
Huvudupphovsmän: Trede, Nikolaus S., Ota, Tatsuya, Kawasaki, Hirohide, Paw, Barry H., Katz, Tammisty, Demarest, Bradley, Hutchinson, Sarah, Zhou, Yi, Hersey, Candace, Zapata, Agustin, Amemiya, Chris T, Zon, Leonard I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2551557/
https://ncbi.nlm.nih.gov/pubmed/18729230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21683
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