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Many Ribosomal Protein Mutations Are Associated With Growth Impairment and Tumor Predisposition in Zebrafish
We have characterized 28 zebrafish lines with heterozygous mutations in ribosomal protein (rp) genes, and found that 17 of these are prone to develop zebrafish malignant peripheral nerve sheath tumors (zMPNST). Heterozygotes from the vast majority of tumor-prone rp lines were found to be growth-impa...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2682537/ https://ncbi.nlm.nih.gov/pubmed/19097187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21815 |
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