AAV retinal transduction in a large animal model species: Comparison of a self-complementary AAV2/5 with a single-stranded AAV2/5 vector

PURPOSE: To compare self-complementary (sc) and single-stranded (ss) adeno-associated viral 2/5 (AAV2/5) vectors for retinal cell transduction in the dog when delivered by subretinal injection. METHODS: ScAAV2/5 and ssAAV2/5 vectors encoding enhanced green fluorescent protein (GFP) under control of...

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Main Authors: Petersen-Jones, S.M., Bartoe, J.T., Fischer, A.J., Scott, M., Boye, S.L., Chiodo, V., Hauswirth, W.W.
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Vision 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743804/
https://ncbi.nlm.nih.gov/pubmed/19756181
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