A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer

Human colorectal cancers (CRCs) display a large number of genetic and epigenetic alterations, some of which are causally involved in tumorigenesis (drivers) and others that have little functional impact (passengers). To help distinguish between these two classes of alterations, we used a transposon-...

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Detalhes bibliográficos
Main Authors: Starr, Timothy K., Allaei, Raha, Silverstein, Kevin A. T., Staggs, Rodney A., Sarver, Aaron L., Bergemann, Tracy L., Gupta, Mihir, O’Sullivan, M. Gerard, Matise, Ilze, Dupuy, Adam J., Collier, Lara S., Powers, Scott, Oberg, Ann L., Asmann, Yan W., Thibodeau, Stephen N., Tessarollo, Lino, Copeland, Neal G., Jenkins, Nancy A., Cormier, Robert T., Largaespada, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743559/
https://ncbi.nlm.nih.gov/pubmed/19251594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1163040
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