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New methods for finding common insertion sites and co-occurring common insertion sites in transposon- and virus-based genetic screens

Insertional mutagenesis screens in mice are used to identify individual genes that drive tumor formation. In these screens, candidate cancer genes are identified if their genomic location is proximal to a common insertion site (CIS) defined by high rates of transposon or retroviral insertions in a g...

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Autors principals: Bergemann, Tracy L., Starr, Timothy K., Yu, Haoyu, Steinbach, Michael, Erdmann, Jesse, Chen, Yun, Cormier, Robert T., Largaespada, David A., Silverstein, Kevin A. T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351147/
https://ncbi.nlm.nih.gov/pubmed/22241771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1295
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