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Formation of an active site in trans by interaction of two complete Varkud Satellite ribozymes

The complete VS ribozyme comprises seven helical segments, connected by three three-way RNA junctions. In the presence of Mg(2+) ions, cleavage occurs within the internal loop of helix I. This requires the participation of a guanine (G638) within the helix I loop, and a remote adenine (A756) within...

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Detalhes bibliográficos
Main Authors: Ouellet, Jonathan, Byrne, Max, Lilley, David M.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743049/
https://ncbi.nlm.nih.gov/pubmed/19703941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1759009
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