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Hepatitis C Virus Immune Escape via Exploitation of a Hole in the T cell Repertoire

Hepatitis C virus (HCV) infection frequently persists despite eliciting substantial virus-specific immune responses. Thus, HCV infection provides a setting in which to investigate mechanisms of immune escape that allow for viral persistence. Viral amino acid substitutions resulting in decreased MHC...

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Hlavní autoři: Wolfl, Matthias, Rutebemberwa, Alleluiah, Mosbruger, Timothy, Mao, Qing, Li, Hongmei, Netski, Dale, Ray, Stuart C., Pardoll, Drew, Sidney, John, Sette, Alessandro, Allen, Todd, Kuntzen, Thomas, Kavanagh, Daniel G., Kuball, Jurgen, Greenberg, Philip D., Cox, Andrea L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742502/
https://ncbi.nlm.nih.gov/pubmed/18941234
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