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Use of CD137 to study the full repertoire of CD8+ T cells without the need to know epitope specificities
CD137 (4-1BB) is a member of the TNFR-family with co-stimulatory function, triggering pro-survival signals in activated T-cells. Upregulation of CD137 upon stimulation allows identifying and isolating live, human antigen-specific CD8+ T-cells of all phenotypes and therefore provides a comprehensive...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784669/ https://ncbi.nlm.nih.gov/pubmed/18561198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20594 |
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