Cellular immune selection with hepatitis C virus persistence in humans

Hepatitis C virus (HCV) infection frequently persists despite substantial virus-specific cellular immune responses. To determine if immunologically driven sequence variation occurs with HCV persistence, we coordinately analyzed sequence evolution and CD8(+) T cell responses to epitopes covering the...

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Hlavní autoři: Cox, Andrea L., Mosbruger, Timothy, Mao, Qing, Liu, Zhi, Wang, Xiao-Hong, Yang, Hung-Chih, Sidney, John, Sette, Alessandro, Pardoll, Drew, Thomas, David L., Ray, Stuart C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213263/
https://ncbi.nlm.nih.gov/pubmed/15939790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050121
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