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Gambogic acid covalently modifies IκB-kinase-β subunit to mediate suppression of lipopolysaccharide-induced activation of NF-κB in macrophages

Gambogic acid (GA) is a polyprenylated xanthone abundant in the resin of Garcinia morella and G. hanburyi with a long history of use as a complementary and alternative medicine. The anti-tumor activity of GA has been well demonstrated and is thought to arise partly from the associated anti-inflammat...

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Hlavní autoři: Palempalli, Umamaheshwari D., Gandhi, Ujjawal, Kalantari, Parisa, Vunta, Hema, Arner, Ryan J., Narayan, Vivek, Ravindran, Anand, Prabhu, K. Sandeep
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741425/
https://ncbi.nlm.nih.gov/pubmed/19140805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081482
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