Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib

Celecoxib is a selective cyclooxygenase (COX)-2 inhibitor used to treat inflammation, while selenium is known to down-regulate the transcription of COX-2 and other pro-inflammatory genes. To expand the anti-inflammatory property, wherein celecoxib could inhibit pro-inflammatory gene expression at ex...

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Detalhes bibliográficos
Main Authors: Desai, Dhimant, Kaushal, Naveen, Gandhi, Ujjawal H., Arner, Ryan J., D’Souza, Christopher, Chen, Gang, Vunta, Hema, El-Bayoumy, Karam, Amin, Shantu, Prabhu, K. Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004533/
https://ncbi.nlm.nih.gov/pubmed/20883674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.09.021
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