Carregant...
Targeting of Histone Acetyltransferase p300 by Cyclopentenone Prostaglandin Δ(12)-PGJ(2) through Covalent Binding to Cys(1438)
[Image: see text] Inhibitors of histone acetyltransferases (HATs) are perceived to treat diseases like cancer, neurodegeneration, and AIDS. On the basis of previous studies, we hypothesized that Cys(1438) in the substrate binding site could be targeted by Δ(12)-prostaglandin J(2) (Δ(12)-PGJ(2)), a c...
Guardat en:
| Autors principals: | , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312006/ https://ncbi.nlm.nih.gov/pubmed/22141352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200383c |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|