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Cyclopentenone Prostaglandins PGA(2) and 15-Deoxy-Δ(12,14) PGJ(2) Suppress Activation of Murine Microglia and Astrocytes: Implications for Multiple Sclerosis

The cyclopentenone prostaglandin (cPG) 15-deoxy-Δ(12,14)-PGJ(2) (15d-PGJ(2)) has been identified as a potent antiinflammatory agent that is able to inhibit the activation of macrophages and microglia. Additionally, 15d-PGJ(2) is able to ameliorate the clinical manifestations of experimental autoimmu...

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Detalhes bibliográficos
Main Authors: Storer, Paul D., Xu, Jihong, Chavis, Janet A., Drew, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819749/
https://ncbi.nlm.nih.gov/pubmed/15723383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.20413
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