Thioredoxin Reductase-1 Negatively Regulates HIV-1 Transactivating Protein Tat-dependent Transcription in Human Macrophages

Epidemiological studies suggest a correlation between severity of acquired immunodeficiency syndrome (AIDS) and selenium deficiency, indicating a protective role for this anti-oxidant during HIV infection. Here we demonstrate that thioredoxin reductase-1 (TR1), a selenium-containing pyridine nucleot...

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Détails bibliographiques
Auteurs principaux: Kalantari, Parisa, Narayan, Vivek, Natarajan, Sathish K., Muralidhar, Kambadur, Gandhi, Ujjawal H., Vunta, Hema, Henderson, Andrew J., Prabhu, K. Sandeep
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Transcription, Chromatin, and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586244/
https://ncbi.nlm.nih.gov/pubmed/18835810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807403200
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