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Characterization of the kinase activity of a WNK4 protein complex
Mutations in WNK4 protein kinase cause pseudohypoaldosteronism type II (PHAII), a genetic disorder that is characterized by renal NaCl and K(+) retention leading to hypertension and hyperkalemia. Consistent with this, WNK4 is known to regulate several renal tubule transporters, including the NaCl co...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739714/ https://ncbi.nlm.nih.gov/pubmed/19587141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00358.2009 |
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