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Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Gαs protein

Mechanical stresses that are preferentially transmitted across the cell surface via transmembrane integrin receptors activate gene transcription by triggering production of intracellular chemical second messengers, such as cAMP. Here we show that the sensitivity of the cAMP signaling pathway to mech...

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Bibliografische gegevens
Hoofdauteurs: Alenghat, Francis J., Tytell, Jessica D., Thodeti, Charles K., Derrien, Alexandrine, Ingber, Donald E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739599/
https://ncbi.nlm.nih.gov/pubmed/19170051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22001
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