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Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Gαs protein
Mechanical stresses that are preferentially transmitted across the cell surface via transmembrane integrin receptors activate gene transcription by triggering production of intracellular chemical second messengers, such as cAMP. Here we show that the sensitivity of the cAMP signaling pathway to mech...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739599/ https://ncbi.nlm.nih.gov/pubmed/19170051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22001 |
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