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Gαq Reduces cAMP Production by Decreasing Gαs Protein Abundance

The heterotrimeric guanine nucleotide-binding protein Gαq transduces signals from heptahelical transmembrane receptors (e.g., α(1)-adrenergic, endothelin 1A, and angiotensin II) to stimulate generation of inositol-1,4,5-trisphosphate and diacylglycerol. In addition, Gαq decreases cAMP production, th...

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Autors principals: Tang, Tong, Gao, Mei Hua, Miyanohara, Atsushi, Hammond, H. Kirk
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688725/
https://ncbi.nlm.nih.gov/pubmed/18948082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.10.054
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