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ß(1)-Adrenergic Receptor vs Adenylyl Cyclase 6 Expression in Cardiac Myocytes: Differences in Transgene Localization and Intracellular Signaling

Adenylyl cyclase type 6 (AC6) and the ß(1) adrenergic receptor (ß(1)AR) are pivotal proteins in transmembrane ßAR-signaling in cardiac myocytes. Increased expression of AC6 has beneficial effects on the heart, but increased ß(1)AR expression has marked deleterious effects. Why do these two elements...

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Detalhes bibliográficos
Main Authors: Gao, Mei Hua, Tang, Tong, Miyanohara, Atsushi, Feramisco, James R., Hammond, H. Kirk
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815038/
https://ncbi.nlm.nih.gov/pubmed/19932173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.11.010
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