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ß(1)-Adrenergic Receptor vs Adenylyl Cyclase 6 Expression in Cardiac Myocytes: Differences in Transgene Localization and Intracellular Signaling

Adenylyl cyclase type 6 (AC6) and the ß(1) adrenergic receptor (ß(1)AR) are pivotal proteins in transmembrane ßAR-signaling in cardiac myocytes. Increased expression of AC6 has beneficial effects on the heart, but increased ß(1)AR expression has marked deleterious effects. Why do these two elements...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gao, Mei Hua, Tang, Tong, Miyanohara, Atsushi, Feramisco, James R., Hammond, H. Kirk
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815038/
https://ncbi.nlm.nih.gov/pubmed/19932173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.11.010
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