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ß(1)-Adrenergic Receptor vs Adenylyl Cyclase 6 Expression in Cardiac Myocytes: Differences in Transgene Localization and Intracellular Signaling
Adenylyl cyclase type 6 (AC6) and the ß(1) adrenergic receptor (ß(1)AR) are pivotal proteins in transmembrane ßAR-signaling in cardiac myocytes. Increased expression of AC6 has beneficial effects on the heart, but increased ß(1)AR expression has marked deleterious effects. Why do these two elements...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2815038/ https://ncbi.nlm.nih.gov/pubmed/19932173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.11.010 |
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