Activation of PH-domain Leucine-Rich Protein Phosphatase 2 (PHLPP2) by Agonist Stimulation in Cardiac Myocytes Expressing Adenylyl Cyclase Type 6

The Ser/Thr-specific phosphatase PHLPP (pleckstrin homology domain leucine-rich repeat protein phosphatase) regulates the amplitude and duration of agonist-evoked Akt signaling by dephosphorylating the hydrophobic motif (Ser473) of Akt, therefore inactivating Akt. We recently reported that gene tran...

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Hlavní autoři: Gao, Mei Hua, Miyanohara, Atsushi, Feramisco, James R., Tang, Tong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693944/
https://ncbi.nlm.nih.gov/pubmed/19450723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.04.110
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