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α-Latrotoxin Stimulates a Novel Pathway of Ca(2+)-Dependent Synaptic Exocytosis Independent of the Classical Synaptic Fusion Machinery
α-Latrotoxin induces neurotransmitter release by stimulating synaptic vesicle exocytosis via two mechanisms: (1) A Ca(2+)-dependent mechanism with neurexins as receptors, in which α-latrotoxin acts like a Ca(2+) ionophore, and (2) a Ca(2+)-independent mechanism with CIRL/latrophilins as receptors, i...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739239/ https://ncbi.nlm.nih.gov/pubmed/19587270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0898-09.2009 |
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