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α-latrotoxin triggers transmitter release via direct insertion into the presynaptic plasma membrane
α-latrotoxin, a component of black widow spider venom, binds to presynaptic nerve terminals and stimulates massive neurotransmitter release. Previous studies have demonstrated that α-latrotoxin first binds to two high-affinity receptors on nerve terminals, neurexins and CLs (CIRLs and latrophilins),...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313948/ https://ncbi.nlm.nih.gov/pubmed/10880438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3250 |
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