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Rabphilin regulates SNARE-dependent re-priming of synaptic vesicles for fusion

Synaptic vesicle fusion is catalyzed by assembly of synaptic SNARE complexes, and is regulated by the synaptic vesicle GTP-binding protein Rab3 that binds to RIM and to rabphilin. RIM is a known physiological regulator of fusion, but the role of rabphilin remains obscure. We now show that rabphilin...

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Autors principals: Deák, Ferenc, Shin, Ok-Ho, Tang, Jiong, Hanson, Phyllis, Ubach, Josep, Jahn, Reinhard, Rizo, Josep, Kavalali, Ege T, Südhof, Thomas C
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1500841/
https://ncbi.nlm.nih.gov/pubmed/16763567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601165
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